The dubstep star was already on course to become No.1 in this week's mid-week chart.

Released on the Ministry Of Sound label, the single, is the second from the British DJ's third album which has yet to be named.

The single's official video features Albanian Ora dancing in an L.A. park with a group of people.

Elsewhere in the UK singles chart, Emeli Sandé's 'Next To Me' went in at No.2. Last week's No.1 'Someone I Used To Know' by Gotye slipped to No.3.

Whitney Houston's 'I Will Always Love You' went in at No.14, and Houston's 'I Wanna Dance With Somebody' is this week's No.20.

Although Alyssa Reid's 'Alone Again' was due to be confirmed as the best-selling single this week after it pushed ahead in the midweek update, Guetta has jumped in front to secure the top spot. 

The Official Charts Company revealed that Guetta's new anthem outsold Reid's offering, which is now at 2, "by more than 9,000 copies" and has given him a fifth UK No.1. 

Gotye's 'Somebody That I Used To Know' is sitting comfortably at No.3, Jessie J's 'Domino' has dropped a place to No.4 and Flo Rida's 'Wild Ones', which also features Sia, rounds off the Top 5. 

Lana Del Rey, who today landed the UK No.1 spot in the albums chart, is at No.9 with 'Born To Die' and also has 'Video Games' lower down at No.17. 

Watch the music video for 'Titanium' below.