Tuesday, March 1, 2011 9:06pm ET by  
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50 Cent’s movie premiere weekend

Last year 50 Cent lost a shocking 54 pounds for a movie which is set to premiere at the Miami International Film Festival this weekend.

‘Things Fall Apart’ is based on the true story of promising college football player Deon Barnes who was tragically diagnosed with cancer.

Actor Cedric Sanders, who plays 50’s brother in the movie, admits he was thrilled to work with the rapper.

“I’m proud to have been part of this film,” he says. “Working with 50 Cent was truly inspiring. We'd have a break from rehearsals and he would immediately head outside to workout."

Ray Liotta also co-stars. 

Watch 50 Cent talk about his challenging role on ‘The Today Show’ here: