Lady Gaga has expressed her desire to collaborate with Britney Spears.

The idea of the blockbuster duet came about at the weekend when the 'Toxic' lady said in a fan Q&A that she would like to work with the 'Applause' star.

The former X Factor USA judge said: "I would do a duet with Lady Gaga. I think that would be a lot of fun. I think she's very different and interesting and intricate."

It seems the feeling is mutual, with the 'ARTPOP' maestro then tweeting Spears directly: "Lets do this b*tch its time."

It wouldn't be the first big name collaboration Spears has recorded in recent times.

The singer teamed up with woman-of-the-moment Miley Cyrus for the track 'SMS' from the latter's 2013 album 'Bangerz'.

She also worked with will.i.am and sister Jamie Lynn on her eighth record 'Britney Jean'.