American comedian Amy Schumer hosted last night’s MTV Movie Awards (April 12) and took a few pops at some of music and film’s biggest stars.

For her opening monologue, Schumer said:

“Half of you don’t know who I am, and half of you think I’m Meghan Trainor.”

Speaking about Hillary Clinton’s recent announcement of her 2016 presidential bid, she joked:

“After months of speculation, Hillary Clinton today announced… she’s taking Zayn’s spot in One Direction… First woman in One Direction: I never thought I’d live to see the day!”

The comedy star also gave some advice to the night’s victors:

“I don’t want the winners to be worried about the speeches going on too long, because MTV is the only network that refuses to play music.”

The big winner of the night was ‘The Fault In Our Stars’ which was named Movie of the Year and actress Shailene Woodley picked up Best Female Performance for her leading role. Woodley and her co-star Ansel Elgort also shared the Best Kiss prize.

However, Amy Schumer also took aim at the teen romance film: “They should have gone with the original title: ‘Cancer Schmancer’.”

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Watch footage from the 2015 MTV Movie Awards below: